PREVPAC is designed to eliminate H. pylori to reduce the risk of duodenal ulcers from coming back.

What Are Ulcers?

An ulcer in your digestive tract is like an open sore. The top layer(s) of tissue has eroded and the resulting sore is hollowed out like a crater. Two common types of ulcers are duodenal ulcers (ulcers in the first part of the intestine) and stomach ulcers.

Abdominal pain can be a symptom of an ulcer.

Learn more about ulcers:

Different Ulcers. Different Options.

Now doctors realize that there's much more to know about what causes stomach ulcers and duodenal ulcers. Learn about different types of ulcer treatment .

What Are Duodenal Ulcers?

Burning or gnawing pain in your abdomen may be a symptom of a duodenal ulcer.

What Are NSAID-Associated Ulcers?

Learn more about stomach ulcers caused by Nonsteroidal Anti-Inflammatory Drugs (NSAIDs).

Talking To Your Doctor

Only your doctor can determine if you have an ulcer. Talk to your doctor about your ulcer symptoms.

Important Safety Information for Prevacid

If you suffer from persistent heartburn two or more days a week, despite treatment and diet changes, it could be acid reflux disease. Prescription Prevacid Capsules and Prevacid SoluTab^™ (lansoprazole) Orally Disintegrating Tablets are used for the treatment of acid reflux disease including erosive esophagitis and for maintenance of healed erosive esophagitis. Individual results may vary. Most erosions heal in 4–8 weeks. You should not take Prevacid if you are allergic to Prevacid or any of its ingredients. Prevacid may not be right for everyone and has a low occurrence of side effects in adults including diarrhea, abdominal pain, nausea and constipation. Symptom relief does not rule out other serious stomach conditions. Before taking Prevacid, tell your doctor if you are taking ampicillin, atazanavir, digoxin, iron, ketoconazole or warfarin. Talk to your doctor or healthcare provider to see if Prevacid is right for you.

Please see the accompanying Complete Prescribing Information for more information and talk to your healthcare provider.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Important Safety Information for PREVPAC^® (lansoprazole /amoxicillin /clarithromycin)

PREVPAC is indicated for the treatment of patients with H. pylori (Helicobacter pylori) infection and duodenal ulcer disease to eradicate H. pylori. Your results may vary.

The most frequently reported adverse events with PREVPAC were diarrhea (7%), headache (6%) and taste perversion (5%).

Symptomatic response to therapy does not preclude the presence of gastric malignancy.

Eradication of H. pylori reduces the risk of duodenal ulcer recurrence. In patients who fail this therapy, susceptibility testing should be done if possible. If clarithromycin resistance is demonstrated, a non-clarithromycin-containing regimen is recommended.

PREVPAC is not recommended in patients with creatinine clearance less than 30 mL/min. PREVPAC is contraindicated in patients taking cisapride, pimozide, astemizole, terfenadine, ergotamine or dihydroergotamine.

Colchicine toxicity has been reported with concomitant use of clarithromycin and colchicine, especially in geriatric patients; some has occurred in patients with renal insufficiency. Patients should be monitored for clinical symptoms of colchicine toxicity. Clarithromycin may elevate digoxin serum concentrations. Serum digoxin levels should be carefully monitored while digoxin and clarithromycin are taken concomitantly. Clarithromycin should not be used in pregnant women except in circumstances where no alternative therapy is appropriate. Amoxicillin is contraindicated in patients who are allergic to penicillin.

For information about further warnings, precautions or adverse reactions for amoxicillin and clarithromycin, please see the complete prescribing information for amoxicillin and for BIAXIN^® Filmtab^® (clarithromycin tablets, USP).

Please see the accompanying Complete Prescribing Information for Prevacid PREVPAC for more information and talk to your healthcare provider.

BIAXIN Filmtab is not a trademark of Takeda Pharmaceuticals North America, Inc.

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