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PREVPAC is designed to eliminate H. pylori to reduce the risk of duodenal ulcers from coming back.

Ulcer Treatment

Duodenal Ulcers

Millions of people have duodenal ulcers. Men and women of any age can get them. Ulcers tend to feel like a burning or gnawing pain in the abdomen. This pain is sometimes accompanied by a bloated feeling. Nausea may also occur.

What Causes Duodenal Ulcers?
At one time, people believed stress, spicy foods, and family history played a major role in the cause of duodenal ulcers. However, this has not been conclusively proven.

What has been proven is the fact that bacteria called
H. pylori (Helicobacter pylori) are found in up to 90% of patients with duodenal ulcers and are believed to be a major cause of these ulcers. Ulcers can be a recurring problem and can return within one year after healing. But if H. pylori is eliminated, the chances that a duodenal ulcer will recur are greatly reduced.

Important Safety Information for Prevacid

If you suffer from persistent heartburn two or more days a week, despite treatment and diet changes, it could be acid reflux disease. Prescription Prevacid Capsules and Prevacid SoluTabTM (lansoprazole) Orally Disintegrating Tablets are used for the treatment of acid reflux disease including erosive esophagitis and for maintenance of healed erosive esophagitis. Your results may vary. Most erosions heal in 4–8 weeks. Prevacid may not be right for everyone and has a low occurrence of side effects such as diarrhea, abdominal pain and nausea. Symptom relief does not rule out other serious stomach conditions. Talk to your doctor or healthcare professional to see if Prevacid is right for you. Prevacid products should not be crushed or chewed.

Please see the complete Prescribing Information for more information and talk to your doctor.

Important Safety Information for PREVPAC® (lansoprazole /amoxicillin /clarithromycin)

PREVPAC is indicated for the treatment of patients with H. pylori (Helicobacter pylori) infection and duodenal ulcer disease to eradicate H. pylori. Your results may vary.

The most frequently reported adverse events with PREVPAC were diarrhea (7%), headache (6%) and taste perversion (5%).

Symptomatic response to therapy does not preclude the presence of gastric malignancy.

Eradication of H. pylori reduces the risk of duodenal ulcer recurrence. In patients who fail this therapy, susceptibility testing should be done if possible. If clarithromycin resistance is demonstrated, a non-clarithromycin-containing regimen is recommended.

PREVPAC is not recommended for patients with creatinine clearance less than 30 mL/min. PREVPAC is contraindicated in patients taking cisapride, pimozide, astemizole, terfenadine, ergotamine or dihydroergotamine.

Colchicine toxicity has been reported with concomitant use of clarithromycin and colchicine, especially in geriatric patients; some has occurred in patients with renal insufficiency. Patients should be monitored for clinical symptoms of colchicine toxicity. Clarithromycin may elevate digoxin serum concentrations. Serum digoxin levels should be carefully monitored while digoxin and clarithromycin are taken concomitantly. Clarithromycin should not be used in pregnant women except in circumstances where no alternative therapy is appropriate. Amoxicillin is contraindicated in patients who are allergic to penicillin.

For further warnings, precautions or adverse reactions for amoxicillin and clarithromycin, please see the complete prescribing information for amoxicillin and for BIAXIN® Filmtab® (clarithromycin tablets, USP).

Please see the complete Prescribing Information for Prevacid PREVPAC for more information and talk to your doctor.

BIAXIN Filmtab is not a trademark of TAP Pharmaceutical Products Inc.