Beyond the Burn
Prevacid ProductsLearn About PrevacidHeartburnAcid Reflux DiseaseUlcersTools and Resources
Different Ulcers
What are NSAID-Associated Ulcers?
Talking to Your Doctor
Ulcer Treatment
PREVPAC is designed to eliminate H. pylori to reduce the risk of duodenal ulcers from coming back.

Ulcer Treatment

Treatment Options

There is a range of treatment options for ulcers and the associated symptoms. It's best to talk to your doctor about which ulcer medicine might work for you.

H2 blockers get their name from the way they block one particular stimulus of acid production. H2 blockers reduce the amount of acid that is produced in the stomach, but not as much as proton pump inhibitors.

Proton pump inhibitors (PPIs) are a very effective medicine for decreasing stomach acid production.

Prevacid is a proton pump inhibitor. It decreases the production of stomach acid by blocking many of the tiny pumps responsible for acid production. Though results may vary, up to 92% of patients taking one Prevacid a day had healed duodenal ulcers by their fourth week of treatment. For many people, continuing treatment with Prevacid, if prescribed, can stop duodenal ulcers from coming back. Controlled studies did not extend beyond 12 months. Your results may vary.

What is PREVPAC?

PREVPAC (lansoprazole/amoxicillin/clarithromycin) is a convenient daily dose pack that contains a multiple-drug treatment to eliminate Helicobacter pylori (pronounced HELI-co-back-ter pie-LORRIE, abbreviated H. pylori) to reduce the risk of duodenal ulcer recurrence. Each PREVPAC contains daily administration cards for a 10- or 14-day treatment cycle. Each card contains three different prescription drugs for one day's treatment of ulcer medicine. It includes an acid-reducing drug called Prevacid and two antibiotics called amoxicillin capsules, USP and BIAXIN® FILMTAB® (clarithromycin tablets, USP).

Important Safety Information for Prevacid

If you suffer from persistent heartburn two or more days a week, despite treatment and diet changes, it could be acid reflux disease. Prescription Prevacid Capsules and Prevacid SoluTabTM (lansoprazole) Orally Disintegrating Tablets are used for the treatment of acid reflux disease including erosive esophagitis and for maintenance of healed erosive esophagitis. Your results may vary. Most erosions heal in 4–8 weeks. Prevacid may not be right for everyone and has a low occurrence of side effects such as diarrhea, abdominal pain and nausea. Symptom relief does not rule out other serious stomach conditions. Talk to your doctor or healthcare professional to see if Prevacid is right for you. Prevacid products should not be crushed or chewed.

Please see the complete Prescribing Information for more information and talk to your doctor.

Important Safety Information for PREVPAC® (lansoprazole /amoxicillin /clarithromycin)

PREVPAC is indicated for the treatment of patients with H. pylori (Helicobacter pylori) infection and duodenal ulcer disease to eradicate H. pylori. Your results may vary.

The most frequently reported adverse events with PREVPAC were diarrhea (7%), headache (6%) and taste perversion (5%).

Symptomatic response to therapy does not preclude the presence of gastric malignancy.

Eradication of H. pylori reduces the risk of duodenal ulcer recurrence. In patients who fail this therapy, susceptibility testing should be done if possible. If clarithromycin resistance is demonstrated, a non-clarithromycin-containing regimen is recommended.

PREVPAC is not recommended for patients with creatinine clearance less than 30 mL/min. PREVPAC is contraindicated in patients taking cisapride, pimozide, astemizole, terfenadine, ergotamine or dihydroergotamine.

Colchicine toxicity has been reported with concomitant use of clarithromycin and colchicine, especially in geriatric patients; some has occurred in patients with renal insufficiency. Patients should be monitored for clinical symptoms of colchicine toxicity. Clarithromycin may elevate digoxin serum concentrations. Serum digoxin levels should be carefully monitored while digoxin and clarithromycin are taken concomitantly. Clarithromycin should not be used in pregnant women except in circumstances where no alternative therapy is appropriate. Amoxicillin is contraindicated in patients who are allergic to penicillin.

For further warnings, precautions or adverse reactions for amoxicillin and clarithromycin, please see the complete prescribing information for amoxicillin and for BIAXIN® Filmtab® (clarithromycin tablets, USP).

Please see the complete Prescribing Information for Prevacid PREVPAC for more information and talk to your doctor.

BIAXIN Filmtab is not a trademark of TAP Pharmaceutical Products Inc.