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PREVPAC is designed to eliminate H. pylori to reduce the risk of duodenal ulcers from coming back.

Ulcer Treatment

Diagnosing Duodenal Ulcers

Visiting with your doctor is the only way to help diagnose ulcer symptoms. Your doctor may use any of the following tests to help diagnose your condition.

Endoscopy is one of the best diagnostic tools that gastroenterologists have to examine the inside of your upper gastrointestinal tract. For upper GI endoscopy, your doctor can use a tiny fiber-optic camera to visualize and take pictures of the inside of your GI tract. This procedure can also be used to take a tissue sample.

Upper GI series is a common test that x-rays the gastrointestinal (GI) tract, which includes the esophagus, the stomach and the first part of the small intestine. Before the test, you drink barium, a harmless, flavored liquid. Your doctor will be able to visualize your GI tract with x-ray technology, because x-rays do not pass through the barium.

H. pylori testing can be done by several methods. Your doctor may test for the presence of H. pylori bacteria by drawing a sample of your blood, giving you a breath test, or testing a small piece of tissue (or biopsy) taken from your stomach lining during an endoscopy.

Important Safety Information for Prevacid

If you suffer from persistent heartburn two or more days a week, despite treatment and diet changes, it could be acid reflux disease. Prescription Prevacid Capsules and Prevacid SoluTabTM (lansoprazole) Orally Disintegrating Tablets are used for the treatment of acid reflux disease including erosive esophagitis and for maintenance of healed erosive esophagitis. Your results may vary. Most erosions heal in 4–8 weeks. Prevacid may not be right for everyone and has a low occurrence of side effects such as diarrhea, abdominal pain and nausea. Symptom relief does not rule out other serious stomach conditions. Talk to your doctor or healthcare professional to see if Prevacid is right for you. Prevacid products should not be crushed or chewed.

Please see the complete Prescribing Information for more information and talk to your doctor.

Important Safety Information for PREVPAC® (lansoprazole /amoxicillin /clarithromycin)

PREVPAC is indicated for the treatment of patients with H. pylori (Helicobacter pylori) infection and duodenal ulcer disease to eradicate H. pylori. Your results may vary.

The most frequently reported adverse events with PREVPAC were diarrhea (7%), headache (6%) and taste perversion (5%).

Symptomatic response to therapy does not preclude the presence of gastric malignancy.

Eradication of H. pylori reduces the risk of duodenal ulcer recurrence. In patients who fail this therapy, susceptibility testing should be done if possible. If clarithromycin resistance is demonstrated, a non-clarithromycin-containing regimen is recommended.

PREVPAC is not recommended for patients with creatinine clearance less than 30 mL/min. PREVPAC is contraindicated in patients taking cisapride, pimozide, astemizole, terfenadine, ergotamine or dihydroergotamine.

Colchicine toxicity has been reported with concomitant use of clarithromycin and colchicine, especially in geriatric patients; some has occurred in patients with renal insufficiency. Patients should be monitored for clinical symptoms of colchicine toxicity. Clarithromycin may elevate digoxin serum concentrations. Serum digoxin levels should be carefully monitored while digoxin and clarithromycin are taken concomitantly. Clarithromycin should not be used in pregnant women except in circumstances where no alternative therapy is appropriate. Amoxicillin is contraindicated in patients who are allergic to penicillin.

For further warnings, precautions or adverse reactions for amoxicillin and clarithromycin, please see the complete prescribing information for amoxicillin and for BIAXIN® Filmtab® (clarithromycin tablets, USP).

Please see the complete Prescribing Information for Prevacid PREVPAC for more information and talk to your doctor.

BIAXIN Filmtab is not a trademark of TAP Pharmaceutical Products Inc.